If the total day by day dose exceeds 250 mg, it should be supplied in divided doses. Inside a review of adjunctive therapy for intricate partial seizures during which patients were being obtaining either carbamazepine or phenytoin Besides valproate, no adjustment of carbamazepine or phenytoin dosage was essential [see Clinical Scientific tests (14.two)]. Even so, because valproate may perhaps communicate with these or other concurrently administered AEDs and also other prescription drugs, periodic plasma focus determinations of concomitant AEDs are proposed through the early study course of therapy [see Drug Interactions (seven)].
Employing alcohol or tobacco with selected medicines can also lead to interactions to occur. Explore along with your healthcare Experienced the use of your medicine with foodstuff, alcohol, or tobacco.
Certain medicines should not be made use of at or across the time of feeding on foodstuff or ingesting sure different types of foodstuff since interactions may possibly come about.
If a dose is missed it ought to be taken at the earliest opportunity, unless it is sort of time for another dose. If a dose is skipped, the individual must not double the subsequent dose.
Epilepsy is recurrent seizures that will come about without having a identified provoking induce. Febrile seizures can happen in infants and youthful kids who definitely have a…
Taking folic acid supplements right before having pregnant And through early pregnancy can lessen the chance of getting more info a little one with a neural tube defect. If you take Depakote through pregnancy for any health care affliction, your son or daughter is at risk for acquiring decrease IQ and may be in danger for building autism or attention deficit/hyperactivity dysfunction.
Phone your healthcare service provider right away In case you have any of your signs and symptoms listed beneath. Your healthcare supplier may possibly do more exams ahead of And through your cure with DEPAKOTE.
Other side effects not detailed can also arise in some people. For those who observe any other consequences, Verify with your Health care Qualified.
For those with mitochondrial condition: In case you have Alpers-Huttenlocher syndrome or Have a very family members record of this metabolic disorder, you may have the next possibility of liver failure when using divalproex sodium.
have or Feel you have a genetic liver dilemma a result of a mitochondrial condition for instance Alpers-Huttenlocher syndrome.
Protect against migraine head aches. There is no evidence that it works to treat a migraine headache when you already have a single.
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Generally speaking, your physician will continue to keep you at the bottom successful dosage that you’re ready to tolerate with no Uncomfortable side effects.